What Is Evorel Sequi?
Evorel Sequi is a skin patch hormone replacement therapy (HRT) used to aid a woman’s transition into menopause. It helps treat symptoms such as:
- hot flushes
- night sweats
- altered mood
- brain fog
- vaginal irritation/dryness
- irregular menstruation
- diminished libido
- osteoporosis risk
This transitional stage before menopause- perimenopause, is the timepoint in a woman’s life when the hormones, oestrogen and progesterone, start to fall.
Evorel Sequi mimics these natural hormones (oestrogen and progesterone) to help rebalance your hormone levels, alleviating symptoms and helping you feel more well in yourself.
What does Evorel Sequi treat?
Evorel Sequi helps ease the transition into menopause. This transition stage is known as ‘perimenopause’.
But how do you define menopause?
Menopause is a natural stage in a woman’s life when her menstrual cycles end due to declining hormone levels. This typically occurs when a woman reaches the age of 45-55 years and hasn’t experienced a menstrual period for over 12 months.
This means a woman will no longer ovulate, and you begin to lose the functional effects of oestrogen and progesterone.
The falling levels of oestrogen and progesterone can bring about various physical and psychological health changes which impact a woman’s wellbeing and daily life.
These changes include:
- hot flashes
- night sweats
- vaginal dryness
- irritable or low mood
- disrupted sleep
- diminished libido
- the feeling of “not being yourself”
The changes perimenopause brings can be particularly distressing at an already unfamiliar stage in a woman’s life.
Evorel Sequi uses synthetic forms of estradiol and progesterone to restore your hormonal balance and help relieve menopausal symptoms.
How Evorel Sequi Patches Work
Evorel Sequi is a combined HRT which is taken as a transdermal patch (a patch which secretes treatments through the skin). This type of HRT emulates your natural hormonal cycle by releasing oestrogen-only in the first 2 weeks of your cycle and then providing both oestrogen + progesterone in the 3rd and 4th weeks of your cycle.
By “replacing” the hormones which start to fall in perimenopause, Evorel Sequi aims to re-balance hormone levels and alleviate symptoms such as heat flashes, brain fog, altered mood, vaginal dryness/irritation and reduced libido.
Evorel Sequi patches are taken as two types. Evorel 50 is taken in the first two weeks of your cycle and Evorel Conti is taken in weeks 3 & 4.
- Weeks 1-2: Evorel 50, which releases oestrogen-only
- Weeks 3-4: Evorel Conti, which contains both progesterone and oestrogen.
Not only does this pattern mimic your natural body’s hormonal cycle, but the combined progesterone has protective effects against excess oestrogen exposure. Too much oestrogen exposure can increase your risk of getting endometrial or breast cancers so must be taken with caution.
To use these patches, you simply place the correct patch on your thigh or buttocks. Your skin will then absorb the hormone treatment into your bloodstream where it can exert its therapeutic effects.
To understand how Evorel Sequi works, it is important to understand the role of the hormones, oestrogen and progesterone, in normal health.
Oestrogen, Progesterone and Menopause
Both oestrogen and progesterone are essential hormones for reproductive health.
They are the hormones which regulate ovulation and the rest of the menstrual cycle.
That is why when their levels start to fall during menopause, you can begin to experience various health changes.
Oestrogen is important for reproductive health and function.
It promotes growth, structural integrity and secretions of the womb lining and vagina. This is why when oestrogen levels decline during menopause, it leads to vaginal dryness and irritation.
Reduced levels of oestrogen can also cause other systemic symptoms such as night sweats, hot flushes and risk of osteoporosis.
Evorel Sequi utilises oestrogen to counteract these symptoms of menopause.
Oestrogen also has positive health benefits for bodily health, such as improved bone density and strength. This reduces your risk of osteoporosis as you age and makes you less prone to fractures.
Oestrogen is also known to have protective features for your cardiac health.
Progesterone works alongside oestrogen in regulating your cycle and ‘maintains’ the womb lining. Progesterone is usually administered in HRTs to avoid unopposed oestrogen since this can increase your risk of breast and womb cancers.
They are usually combined with progesterone, especially if you still have a uterus, since oestrogen medications can increase your risk of womb cancer.
How to Use Evorel Sequi Patches Correctly
There are two types of patches in a pack: Evorel 50 and Evorel Conti. Evorel 50 is taken in the first two weeks of your cycle and contains oestrogen only.
Evorel Conti is taken in weeks 3 and 4 of your cycle and contains both oestrogen and progesterone.
When to start taking Evorel Sequi:
You can start using Evorel Sequi anytime if you have reached menopause and haven’t started using any other HRTs.
If you are changing from another HRT to Evorel Sequi patches, you should follow the advice of your doctor since some HRTs require a withdrawal period before you can start a new type of HRT.
If you still experience regular periods, then you should apply your first patch (Evorel 50) between days 1 to 5 of your period.
You should then change your patch every 3-4 days, until you reach weeks 3 and 4, when you should start using Evorel Conti patches instead.
Choosing the right location:
To apply a patch, you should ideally place it below the waistband such as on your thighs or buttocks. Never place patches near breasts, or on irritated skin.
Changing your patch:
HRT patches only contain enough hormones to last 3-4 days so you should change your Evorel patch to a new one after every 3-4 days.
Most women find it easier to change patches every Monday and Thursday so it’s easier to remember.
After carefully removing the patch, there may be some adhesive residue left. It should go away on its own, or you can wipe it away using baby oil to help.
Below is a step-by-step summary highlighting how you can effectively apply Evorel Sequi patches.
- Starting in the first week of your cycle, apply an Evorel 50 patch directly to an area of skin on your thighs or buttocks.
- Change your patch every 3-4 days (for example every Monday and Thursday). Remember to apply it to a different area of skin on your thigh/buttock to avoid skin irritation.
- Once it reaches Weeks 3 and 4, start applying Evorel Conti in the same way, changing patches every 3-4 days until your next cycle.
Some helpful tips:
- Most women find it easy to apply patches every Monday and Thursday. This makes it easier to remember and keep track of days too.
- Applying patches to areas below the waist such as on your thighs or buttocks are a safe and effective area of skin. These areas absorb a lot better and allow more effective delivery of the HRT.
- Do not apply patches near your breasts.
- Avoid applying moisturiser directly before applying a patch as it can cause patches to fall off.
- If a patch falls off, immediately replace the patch with a fresh one and change it on your usual patch changing day.
- If you forget to change a patch, change it to a new patch as soon as possible and continue changing it on your usual patch-changing day.
It is as simple as that to make sure you are taking Evorel Sequi correctly and effectively.
Remember to read the package’s instructions and the directions provided by your doctor.
Evorel Sequi Price and Prescription in the UK
Evorel Sequi is a prescriptive treatment, therefore you will need to be approved by your doctor to be able to use it. You also can’t purchase Evorel Sequi over-the-counter, however you can obtain it through the NHS. You will need to discuss this with your GP who will review if this is suitable for you.
You can also obtain an Evorel Sequi prescription online from services such as Meds for Less.
It is simple to order Evorel Sequi online.
All you’ll need to do is complete a health questionnaire, which will be reviewed by one of our medical professionals to see if Evorel Sequi is a suitable treatment for you.
If Evorel Sequi is suitable for you we can deliver it straight to your door, or we can recommend other treatments which will work best for you.
Evorel Sequi price UK:
| 8 patches of HRT (2× patches a week, lasts for 4 weeks) |
£39.00 |
| 16 patches of HRT (2× patches a week, lasts for 8 weeks) |
£59.00 |
This table highlights the standard Evorel Sequi patch pack price.
Who can use Evorel Sequi
Evorel Sequi is typically targeted for women who are still menstruating but experiencing menopausal symptoms. This is usually for women between 40-45 years old during perimenopause.
If you are over the age of 45 years and begin to notice menopausal symptoms, you may also be prescribed Evorel Sequi without requiring further investigations.
Possible Side Effects and Precautions
Side effects:
As with most treatments, Evorel Sequi may cause side effects.
These are typically mild and can present as:
- Nausea
- Headache
- Dizziness
- Breast pain
- Altered mood
- Skin irritation
- Painful periods/heavier bleeds
Side effects typically subside with continued use as your body adjusts to treatment. This may take up to 3 months of usage before side effects subside.
If the side effects you experience are severe or they persist after 3 months, contact your doctor for medical advice.
If you experience the following severe side effects, immediately stop usage and seek immediate medical attention.
- Severe allergic reaction
- Seizures
- Signs of cancer (including unexplained weight loss, abnormal bleeding, nausea/vomiting, lumps or bumps anywhere)
- Jaundice
- Severe migraines
- Drastic rise in blood pressure
If you have any other concerns or have any other reasons consult a doctor or pharmacist to help you. Other reasons to consult your doctor include:
- Patches not sticking properly
- Symptoms not improving after more than 3 months of appropriate usage
- Abnormal blood spotting or vaginal bleeding
- Any other concerns or worries you may have taking HRT
Precautions
Risk of breast or womb cancer with prolonged oestrogen exposure.
Unopposed oestrogen, or prolonged oestrogen exposure can increase your risk of getting breast or endometrial (womb lining) cancers.
If you have a history of other cancers or have relatives who have had breast or endometrial cancer, HRTs like Evorel Sequi may not be suitable for you. It is best to consult your doctor who can best advise you on treatments for menopause.
If you have had a hysterectomy, Evorel Sequi may not be suitable for you. Your doctor may prescribe you oestrogen-only treatments instead.
Evorel Sequi is NOT suitable for you if you:
- have breast cancer or a history of breast cancer
- have other oestrogen sensitive cancers, such as endometrial cancer
- are pregnant
- experience unexplained vaginal bleeding
- have a history of a thrombosis or embolism (blood clot), such as in your legs or lungs
- have a blood-clotting disorder
- have heart conditions
- have liver disease
- are allergic to Evorel Sequi ingredients
- have porphyria
How to Buy Evorel Sequi Patches Online
Evorel Sequi is available by prescription only, therefore you can’t purchase it over the counter. You may also obtain Evorel Sequi on the NHS though it will need to be approved by your doctor via a consultation.
Evorel Sequi buy UK is available online with chosen suppliers. You can purchase Evorel Sequi at Meds for Less.
It is simple to do this online. All you’ll need to do is:
- Complete a brief health questionnaire.
- This will be reviewed by one of our medical professionals to see if Evorel Sequi is a suitable treatment for you. The dosage and method of HRT may also be considered to best meet your individual needs.
- If Evorel Sequi is suitable for you we can deliver it straight to your door, or we can recommend other treatments which will work best for you.
The standard Evorel Sequi cost starts from £39.99 for 8 patches which will last you for 4 weeks (2x patches a week).
