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Weight Loss
Weight Loss is a goal many people have. Whilst most people can control their weight with a healthy diet and exercise, there are some weight loss a range of weight loss aids out there, ranging from herbal supplements and teas through to prescription weight loss
What is Semaglutide?
Semaglutide is a medication available as an injection or tablets, used to treat type 2 diabetes and obesity. Semaglutide helps type-2 diabetics control blood sugar levels by enhancing the release of insulin, thereby lowering blood glucose levels.
This process also slows digestion and reduces appetite therefore making Semaglutide an effective weight-loss treatment.
Types of Semaglutide for Weight Loss
In the U.K the most widely available brands of Semaglutide are Wegovy, Ozempic and Rybelsus.
WeGovy is licensed for weight loss, whilst Ozempic and Rybelsus are primarily used to treat type-2 diabetes.
However on occasion doctors may prescribe Ozempic ‘off-label’ for weight-loss or Rybelsus as an oral Semaglutide weight loss product.
Brand
Licensed to Treat
Formulation
Ozempic
Type 2 Diabetes
Injection
Rybelsus
Type 2 Diabetes
Tablet
WeGovy
Weight loss
Injection
How effective is Semaglutide for weight loss?
Weight loss injection Semaglutide is considered one of the most effective weight loss treatments available.
A 2021 phase 3 clinical trial found a dosage of 2.4mg weekly Semaglutide injection produced a mean weight loss of 14.9%. Far greater than the 2.4% weight loss seen with the placebo.
Are There Any Side Effects of Semaglutide?
Common of very common side effects include:
Appetite decreased; burping; cholelithiasis (gallstones); constipation; diarrhea; fatigue; gastrointestinal discomfort; gastrointestinal disorders; hypoglycaemia (in combination with other antidiabetic drugs, in patients with type 2 diabetes); nausea; vomiting; weight decrease (in type 2 diabetes patients.)
Uncommon:
Pancreatitis acute; tastes altered
Who Should (and Should Not) Take Semaglutide For Weight Loss?
Who Shouldn’t Take Semaglutide:
Semaglutide is a prescription-only medications. Ultimately prescribing decisions are made by doctors on a case-by-case basis. However there are specific groups where Semaglutide for weight management is not recommend. These include (but are not limited to):
Pregnant and Breastfeeding Women: There is limited data on the effects of Semaglutide on pregnant and breastfeeding women, however, animal studies indicate potential risks to the fetus. The manufacturer recommends avoiding Semaglutide for weight loss or type 2 diabetes in pregnant or breastfeeding women.
· Patients with Renal Impairment: The manufacturer advises caution when dealing with certain subsections of patients experiencing renal issues, particularly those patients undergoing dialysis sessions.
Semaglutide for Weight Loss is recommended for patients with a BMI of 30kg/m2 (or 27kg/m2 where there is at least one weight-related co-morbidity.) You can calculate your BMI using the calculator on the NHS website.
Those with a BMI of 30kg/m2 BMI or greater would be consider clinically obese and likely to be considered with Semaglutide weight loss UK treatment.
An alternative weight management medication is Orlistat (Xenical.) Studies on Orlistat do show clinically significant weight loss results. However Semaglutide is shown to be more effective than Orlistat (Xenical)
Mounjaro (Tirzepatide) is another popular weight loss treatment. Mounjaro activates two hormones that help control appetite and blood sugar. WeGovy works similarly but only targets one of those hormones, making Mounjaro potentially more effective.
Semaglutide for Weight Loss is recommended for patients with a BMI of 30kg/m2 (or 27kg/m2 where there is at least one weight-related co-morbidity.)
Those with a BMI of 30kg/m2 BMI or greater would be consider clinically obese and likely to be considered with Semaglutide weight loss UK treatment.
Clinical studies shows a reduction of 4% in body weight after 3 months and 9% after 6 months amongst those taking subcutaneous Semaglutide injections for weight loss.
Whilst weight loss varies person to person, patients can expect to start ‘seeing’ noticeable reductions in key measurements such as BMI and weight after 3-6 months
In the UK Semaglutide is a prescription-only medication. You can buy Semaglutide for weight loss at Meds for Less after completing a short text based consultation with a doctor.
Semaglutide is a prescription only medications, so dosing is at the prescribing doctors discretion however, a typical WeGovy treatment plan may look something like:
· If well-tolerated, maintain dosage at 2.4mg once a week.
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