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Premique

Premique is a type of combined continuous hormonal replacement therapy. It is typically used to treat symptoms of menopause (e.g night sweats, hot flushes) while providing protection for the uterine (womb) lining. In some cases, premique may also help support bone health after menopause if other options are not appropriate. Read on as we discuss some commonly asked questions about this medication. Please note that it is a prescription-only medication and it is important to discuss your symptoms with a doctor before starting any hormonal replacement therapy.

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What Are Premique Tablets?

Premique tablets are a type of hormone replacement therapy (HRT) used in treating the symptoms of menopause. Each Premique tablet contains two hormones: a form of oestrogen (conjugated oestrogens) and a progestogen (medroxyprogesterone acetate).

What Is Premique HRT Used For?

Premique HRT is primarily used to manage symptoms of menopause such as night sweats, vaginal dryness, and hot flushes. If you are experiencing any of these, you are not alone. Menopausal symptoms can be very uncomfortable and disturbing to daily quality of life but luckily there are several treatment options available.

Additionally, in some cases premique tablets can be used to help prevent osteoporosis (very low bone density) in high risk women post-menopause if other medications are not suitable.

How Do Premique Tablets Work?

So as mentioned, Premique tablets are used to treat symptoms of menopause. Therefore, in order to understand how Premique tablets work, it may be helpful to have an understanding of what happens in menopause. The crucial thing that causes the classic symptoms of night sweats, hot flushes, and vaginal dryness is the decline in oestrogen and progestogen. The drop in these hormones is natural but it may lead to uncomfortable symptoms. Thus, what Premique HRT aims to do is to relieve symptoms by supplementing the hormones that have (naturally) severely decreased. More specifically:

  • The oestrogen component helps to relieve night sweats, hot flushes, vaginal dryness, and other menopausal symptoms
  • The progestogen component is very important for women who still have a uterus (womb). By adding progestogen, it protects the womb lining from abnormal growth that can happen from oestrogen supplementation. This is because abnormal growth of the uterine lining could increase the risk of endometrial cancer.

Who Can Take Premique?

Premique is best suited to women who are experiencing moderate to severe menopausal symptoms and have a uterus. However, it is always best to consult a GP or your healthcare provider before starting any hormone replacement therapy like Premique. This is because in some cases, Premique may not be safe or suitable for certain groups. At your HRT consultation, please inform your doctor of any medical history or current medications you take. Some examples where Premique may not be safe include:

  • Women with past or current breast cancer
  • Women with past or current endometrial cancer
  • Blood clotting problem
  • Liver disease
  • Pregnant women
  • Breastfeeding women

How to Take Premique Tablets?

To take Premique tablets safely and for optimal benefit, you should:

  • Take one tablet a day
  • Try to take the Premique tablet at a similar time every day
  • Premique is a ‘continuous’ HRT so there is no gap between packs where you stop taking the tablets
  • It does not matter if you take it with or without food
  • Take the tablets according to your doctor’s instructions and attend your scheduled medication reviews. If you notice side effects or you feel it is not working, consult your doctor. Do not stop the tablets or change the dose by yourself.

Side Effects of Premique

Like all medication, Premique does come with a small risk of side effects that you should be aware of. Some more common ones include:

  • Feeling like your breasts are tender
  • Nausea
  • Headaches
  • Weight changes
  • Mood changes

Some more serious side effects include:

  • Blood clots
  • Increased risk of stroke
  • Increased risk of breast cancer

If you feel worried about possible side effects or you notice some unusual symptoms, please consult your GP promptly.

Premique Warnings & Safety Precautions

While Premique is generally an effective medication for relieving menopausal symptoms, there are still some warnings and safety precautions you should know. These include:

  • Attending your regularly scheduled medication reviews with your doctor. They will assess your response to your treatment and modify the plan if needed. The approach to HRT is to be on the lowest effective dose for the shortest time needed.
  • Look out for signs of cancer, blood clots, and stroke.
  • Before starting premique hrt, let your doctor know about any medical history or family medical history you have. Some important conditions to point out include any cancer or cardiovascular conditions.

Premique Prices in the UK

Depending on where you get Premique, the prices can vary in the UK. If you get it on an NHS prescription for example, it will cost the standard £9.65. If you get Premique privately, the cost will vary depending on the provider but it is usually between £15 to £30 for a pack.

Where to Buy Premique Online in the UK?

Many provider offer premique online in the UK. However, before you make an online purchase, make sure it is a reputable online provider and that they require you to have an online consultation or a valid prescription for Premique.

Unlike sequential HRT which induces a light monthly bleed, Premique is a type of continuous HRT which means you take it daily (no break). This also means you are unlikely to have a monthly bleed when taking Premique. 

In some cases yes, Premique can support long-term bone health after menopause, specifically to prevent something called osteoporosis. However, this is not the main use for Premique, it is important to consult a doctor to discuss your concerns if you are seeking support for bone health.

Yes, if you order Premique online from a reputable provider that provides an online consultation or requires a prescription, then it is likely to be safe. Otherwise, it may be best to visit a GP.

Missing a dose occasionally does not come with dangerous risks but frequently missing doses can make your treatment less effective. If you forget one dose, simply take it as soon as you remember, if it is too close to the time of your next dose then skip the missed dose. Do not take double the dose to make up for the missed one. 

There is significant variation between individuals. Some users report weight gain or low mood while others find that Premique tablets improve their mood.

In comparison to alternative HRT options in the UK, Premique can be considered mid-range in terms of cost. Patches may be more expensive than Premique while tablets that only contain oestrogen may be cheaper.

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