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Progynova is a type of Oral hormone replacement therapy that uses Estradiol Valerate ( a natural form of the oestrogen hormone) to replace falling oestrogen levels, achieve hormonal balance and relieve menopausal symptoms.
Troublesome symptoms of menopause that Progynova can be used to relieve include: Hot flushes, sleep disturbances, mood swings, Urogenital itching and dryness. Progynova can also be used to reduce menopause related bone thinning (osteoporosis) and can be used for the purposes of preserving cardiovascular health.
You can now order Progynova from Meds For Less online and we can deliver this form of HRT safely, reliably and conveniently to your home address within 24 hours.
*Product images are for illustrative purposes only, and you may receive a different licensed alternative.
£29.99
For more information on other form of HRT options (including Progynova patches), you can consult our website, browse medicines and their costs, and place the orders that are right for you.
Progynova is a form of oral Hormone replacement Therapy that uses a natural form of oestrogen (estradiol valerate) to replace falling hormone levels in the body during menopause and relieve menopausal symptoms.
Its main purpose is to relieve symptoms of oestrogen deficiency in post-menopausal women, such as:
Progynova can also be used to reduce the risk of osteoporosis (bone thinning) in post-menopausal women.
For women who still have a uterus, Progynova is usually taken alongside progesterone to protect the uterus and reduce the risk of uterine issues such as endometrial hyperplasia (overgrowth).
Progynova tablets are a form of Oral HRT that contains estradiol valerate ( a natural form of the oestrogen hormone).
These tablets are used to replace the falling oestrogen levels in post-menopausal women and relieve symptoms of menopause, such as:
In addition to using the tablets to replace falling oestrogen levels after menopause and treating oestrogen deficiencies, Progynova can also be used to prevent bone thinning (osteoporosis). After menopause, the fall in oestrogen levels can cause bone thinning, and sometimes Progynova HRT may be prescribed to reduce this effect and preserve bone density.
Progynova contains estradiol valerate (a natural form of the oestrogen hormone), which is normally produced by the ovaries. In menopause, the ovaries stop producing such hormones and oestrogen levels in the body fall. This leads to symptoms of menopause.
Progynova HRT aims to replace the lost oestrogen in the body during menopause with the bio-similar hormone (Estradiol Valerate) and relieve symptoms such as:
The oestrogen in Progynova also circulates in the uterus and vaginal tissues. It relieves the dryness, thinning, and discomfort caused by menopause and eases any other urogenital symptoms.
Oestrogen also has a protective effect on bone strength and bone density. The falling levels during menopause can cause osteoporosis (bone thinning). Progynova increases these oestrogen levels and strengthens bones and bone density.
Progynova is available in 2 main strengths:
Both these doses contain the natural hormone Estradiol Valerate ( a form of oestrogen).
The dose to be taken is chosen based on the severity of menopausal symptoms and one’s individual response to treatment.
Menopause treatment with Progynova usually begins with a standard dose of 1mg (tablet to be taken once a day). It is typically increased to 2mg if further symptom control is required, under medical supervision.
Progyonva will be prescribed at a dosage of either 1mg or 2mg, depending on individual tolerance and symptom severity.
It is to be taken at exactly the dosage prescribed, with one tablet daily at roughly the same time. This tablet is to be swallowed with water, not chewed or crushed. The Progynova tablet can be taken either with or without food.
Progynova tablets should be taken continuously with no breaks between packs. A new pack should be started as soon as the old one is finished.
For women who still have a uterus, Progynova should be taken with progesterone supplementation to protect the uterine lining from any signs of overgrowth (endometrial hyperplasia). A course of progesterone for 12-14 days a month is normally prescribed alongside Progynova for this purpose.
If you miss your dose of Progynova and it has been less than 12 hours since your intended dose, take the pill as soon as you remember. If it has been more than 12 hours since you were supposed to take your dose, skip the missed dose and take the next one on time. Do not double up on Progynova on any particular day to compensate for a missed dose. Please be advised that missing more than one table can sometimes cause breakthrough (period-like bleeding).
The following is an overview of some of the side effects of taking Progynova and some precautions to take while using this form of HRT.
Like all hormonal medications, some side effects occur with Progynova usage. Most of these are mild side effects that disappear with continued use; however, some rarer ones tend to be more severe.
Common but mild side effects of Progynova:
Less common but more moderate-severe side effects:
Serious side but rare side effects:
If you experience any of these, please stop taking Progynova and seek medical help immediately
Precautions and safety information alongside Progynova usage:
Women who have a uterus (who have not had a hysterectomy) should use progesterone cover alongside Progynova to ensure a safe endometrial lining.
Women who have the following conditions should not take Progynova:
If you have any specific concerns about safety and side effects to do with Progynova, please consult with your healthcare provider.
Please find below the Progynova price UK options offered by Meds For Less.
Table 1: Prices for Progynova Buy from Meds For Less
| Progynova dosage | Price per packet (28 tablets) | |
| 1mg | £29.99 | |
| 2mg | £29.99 | |
Progynova and Zumenon are both forms of oral estrogen that are used in Hormonal Replacement Therapy (HRT). They both contain differing variants of the estradiol hormone.
Progynova contains estradiol valerate
Zumenon contains estradiol hemihydrate.
Estradiol Valerate in Progynova is an oestrogen prodrug that the body must convert into active estradiol.
Estradiol hemiydrate in Zumenon is a form of oestrogen that is much closer to the form that is already in the body.
Both these forms of estradiol are very similar and work in the same way in the body. They are not chemically identical but are used to achieve the same effect (delivering oestrogen after menopause).
Their side effect and safety profiles are very-alike however, individual experiences with either medicine can vary due to their differences in absorption/metabolism.
Yes, Progynova can be used in fertility treatments, but not as a standalone medication. It is used more for supplementation purposes.
Progynova’s active ingredient is Estradiol Valerate (a natural form of the oestrogen hormone). Estradiol valerate thickens the uterine lining and makes the womb more receptive to implant an embryo when needed.
Progynova uses in fertility treatment are as follows:
Progynova does not stimulate ovulation and hence it can be used to treat anovulation (lack of ovulation), triggering or stimulation of ovulation.
Dosages, timing and monitoring individual response are important in fertility treatments. Hence please ensure that you are under regular and consistent medical supervision when using Progynova for these purposes.
Progynova contains estradiol (a natural form of oestrogen), which influences different tissues in the body, including skin and hair. The individual effect varies from person to person for Progynova, but some common effects include:
Table 1: Effects of Progynova on the Skin/Hair
Progynova effects on the skin | Progynova effects on the hair |
Improved skin hydration – The skin can feel more hydrated, smoother | Reduced hair thinning and reduced hair fall due to oesotrogen’s protective effect on hair follicles |
Increased collagen production – Increases skin firmness and elasticity. Decreases skin thinning | Enhanced hair quality due to oestrogen giving the impression of shinier or fuller hair |
Reduced skin wrinkling due to increased hydration and collagen support. | Reduced body hair – leading to finer and reduced body hair growth in certain individuals. |
For more specifics on the ancillary effects of Progynova (such as on skin or hair) – please speak to your healthcare advisor.
Progynova can be taken under the age of 40 if a woman is experieicng early/ premature menopause. HRT such as Progynova is usually recommended for premature menopause.
Premature menopause (before 40) occurs when oestorgen levels drop too soon. The body is still used to a certain amount of oestrogen production and this sudden unanticipated drop can cause problems such as:
Progynova during early menopause helps increase levels of estradiol (oestrogen) to normal levels and relieves symptoms of menopause, as well as protecting long-term health.
If you are experieicng symptoms of premature menopause, please consult with your healthcare advisor.
Yes, Progynova can interact with thyroid medication (especially Levothyroxine). This interaction is not dangerous, but it can impact how the thyroid medicine works.
Oral oestrogen tablets such as Progynova can cause metabolic effects in the body, which inactivate free-floating thyroid hormone in the body’s bloodstream. This makes thyroid hormonal mimicking medications like levothyroxine less effective.
This might mean that a higher dose of Levothyroxine is required for patients who are taking it to achieve a similar effect. While on both medications, doctors typically recommend checking Thyroid Simulating Hormone Levels (TSH Levels) or T4 (Thyroxine) levels at least 6-8 weeks after starting Progynova. This helps illustrate how Levothyroxine patients are coping with the influx of Progynova.
If you are taking any type of thyroid medication (especially Levothyroxine) alongside Progynova (or any other HRT) – please consult with your healthcare provider about chances of medication interaction and any dose adjustments you may need.
Yes, Progynova can delay /reduce menopause symptoms if started early; however, it is important to understand the complexities of such a case.
Menopause is a biological state brought on by a decrease in circulating oestrogen as the ovaries stop producing oestrogen. Progynova medicine contains estradiol (a natural form of the oestrogen hormone). If Progynova is taken before menopause, it supplements the falling oestrogen levels in the body, and this can prevent or greatly reduce any menopause symptoms that would appear due to hormonal decline.
If Progynova is started early (before menopause), this prevents the sudden drop in oestrogen levels that occurs during menopause. This, in turn, prevents troublesome symptoms of menopause and helps by:
A woman under the age of 45 experiencing premature menopause starting early oestrogen HRT with progynova can experience the following benefits to their long-term health:
It is important to note that early Progynova usage does not delay actual menopause. There is a natural decline in the amount of oestrogen that the ovaries produce; however, early Progynova usage does mask symptoms and make the transition to menopause easier.
Please speak to your healthcare advisor before starting early Progynova treatment for pre-menopause.
Yes, Progynova pills can and is used by a large number of people for a duration of more than 5 years. However, whether you should personally use it depends on factors such as individual response to treatment, age, and your health (medical history). The following is an overview of safety when Progynova is used for more than 5 years.
Long-term (10-15 yrs) use of Progynova is considered safe if the woman is under 50 and experiencing premature or early menopause. Using oestrogen-based HRT, such as Progynova, is usually recommended in such situations, as it achieves positive effects like protecting bone density and supporting heart health.
Additionally, for healthy women without a history or family history of breast/ovarian cancer, blood clots or heart attacks/ strokes, long-term Progynova usage can still be safe if the lowest-effective dose is used. In such women with no major risk factors, Progynova can be used for a prolonged period of time, provided there are periodic health checks with a healthcare provider to make sure there are no adverse risks and complications to health that are developing.
If you have a personal or family history of breast cancer or blood-clotting episodes and are planning to take oestrogen-based HRT such as Progynova for more than 5 years, please conduct a full medical review with your healthcare provider.