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Sildenafil

Sildenafil Citrate is an Erectile Dysfunction medication. It helps men get an erection by increasing blood flow to the penis. Sildenafil tablets should be taken 30-60 minutes before sex and last for up to 4 hours.

Sildenafil was formally sold under the Viagra brand but is now available as a generic medication, meaning it’s much more affordable.

In the United Kingdom, sildenafil is a prescription only medication, however nowadays, you can buy sildenafil online safely and conveniently at Meds for Less.

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What is Sildenafil?

Sildenafil is a medicine used to treat Erectile Dysfunction (ED) in men. It works by increasing blood flow to the penis to allow for easier erections when sexually aroused.

Sildenafil comes as an oral tablet that can be taken “on-demand”, 30 minutes – 1 hour before planned sexual activity. It stays active in the body for 4-6 hours after ingestion allowing for easier erections during that time frame.

You can now purchase Sildenafil tablets online easily, safely, reliably and conveniently from meds for less and have them delivered to your home address within 24 hours.

Sildenafil is the active ingredient in the branded medication (Viagra) which is used to treat Erectile Dysfunction (ED) and allows for easier erections.

Sildenafil belongs to a class of ED medications called phosphodiesterase-5 inhibitors. It works by increasing blood flow to the penis allowing for easier and more spontaneous erections when sexually aroused.

Sildenafil can be swallowed orally with or without food, along with a full glass of water. After ingestion it stays active in the body for 4-6 hours, allowing for more spontaneous erections during that time frame.

How does Sildenafil work?

Sildenafil inhibits an enzyme called phosphodiesterase-5 which allows the blood vessels supplying the penis to relax and more blood to flow to the penis. This allows a firmer and more spontaneous erection when sexually aroused.

Sildenafil begins working 30-60 minutes after you take it and stays active in the body for 4-6 hours after ingestion allowing easier and more spontaneous erections during this time frame.

Sildenafil 25 mg Dosage

The prescribed dosage Sildenafil should be taken orally 30-60 minutes before planned sexual activity and it can remain effective for 4-6 hours after ingestion. This will allow you to have a spontaneous and easier erection when sexually aroused within this time frame.tab sildenafil 25 mg

Do not take more than one dose of Sildenafil within a 24 hour time period as this can increase the risk of side effects.

Sildenafil should be swallowed whole with a glass of water. It can be taken with or without food, however, avoid heavy or fatty meals as this can interfere with its effectiveness.

When taking Sildenafil you should also limit alcohol consumption as it can decrease the effectiveness of the drug and increase the risk of side effects.

Sildenafil Pills: Possible Side Effects to Know

The standard dose of Sildenafil is 50mg, that is taken orally one hour before anticipated sexual activity. The dose can vary from the minimum (25mg) to the maximum (100mg) depending on how effective and tolerated Sildenafil is for each individual person.

Higher doses are associated with increased risk of side effects. Please speak to your healthcare provider about whether Sildenafil 25mg tablet or a higher dose is appropriate for you.

Sildenafil warnings

Sildenafil is generally safe to use when prescribed however it does come with some warnings and precautions to ensure it’s safety.

The Erectile Dysfunction (ED) pill sildenafil has some contraindications, which means it should be taken if you have the following medical conditions or are taking any of these medicines:

  • If you are taking Nitrates such as those used for chest pain (glyceryltrinitrate, isosorbide mono-nitrate, or nitroglycerin)
  • If you are taking alpha-blockers for either high blood pressure or prostate issues (tamulosin)
  • If you are taking any other ED pills such as Tadalafil or Avanafil
  • If you have a heart condition
  • If you have low or high blood pressure (hypo or hypertension)
  • If you have severe liver, kidney or vision problems

Some serious side effects to watch out for include:

  • A priapism – an erection that lasts more than 4 hours, this is a medical emergency and must be treated immediately to avoid permanent damage to the penis.
  • Allergic reactions such as a rash, swelling of the lips, throat, severe dizziness or an anaphylactic shock

Some activities to avoid when taking ED pills like Sildenafil are the operation of heavy machinery or the consumption of more than mild amounts of alcohol.

Who Can Use Sildenafil Citrate 25 mg Tablets?

Although not everyone who takes the tablets Sildenafil will experience side effects, however, some people do. The side effects of Sildenafil become more likely with increased dosage, please speak to your healthcare provider about what dose may be correct for you.

Some of the more common side effects of Sildenafil are given below:viagra sildenafil 25 mg

  • Headaches
  • Dizziness
  • Indigestion
  • Feeling Sick
  • Facial flushing
  • Vision disturbance
  • Stuffy nose

The more uncommon side effects of Sildenafil (affecting 1 in 100 people) are:

  • Eye discomfort
  • Eye pain
  • Chest pain
  • Drowsiness
  • Dry mouth
  • Changes in blood pressure
  • Nose bleeds
  • Tiredness
  • Vomiting
  • Altered Heartbeat
  • Ear-ringing

Very rare side effects of Sildenafil (Which affect 1 in 1000 people) include:

  • Fainting
  • Hearing impairment
  • Sudden visual impairment
  • Seizure
  • Allergic reactions (difficulty breathing, wheezing, swollen eyelids, face, lips and tongue)

If you have any of the following, stop taking Sildenafil and seek medical attention immediately:

  • Chest pain
  • Allergic reactions ((difficulty breathing, wheezing, swollen eyelids, face, lips and tongue)
  • Prolonged painful erections (priapism)
  • Sudden loss of vision
  • Seizures
  • Sudden skin reaction

Side effects of Sildenafil are usually mild and should last a few hours or up to a day, mild headaches can last upto a week. The side effects of Sildenafil a usually wear off with the effect of the drug.

Please speak to your healthcare provider if you have any concerns about Sildenafil and its side effects.

Sildenafil Pills: Possible Side Effects to Know

Sildenafil is typically safe and suitable to use as an ED in men who have no other health issues. It can be used in men of various ages but it’s typically used in men over 40 who have erectile dysfunction.

Sildenafil is meant to be taken once a day, taking more than one pill a day can increase the risk of side effects, particularly the painful prolonged erection (the priapism).

There are some contra-indications for Sildenafil, which mean you should not be taking the drug if you have any of the following:

  • If you are taking Nitrates for a heart condition or chest pain
  • If you have severe cardiovascular conditions like a recent heart attack (less than 6 months), recent stroke, uncontrolled high or low blood pressure or if you have chronic heart failure
  • If you have hereditary genetic disorders
  • If you have non-atretic anterior ischemic optic neuropathy

Please speak to your healthcare advisor about whether it is safe and suitable for you to use Sildenafil

Warnings and Precautions

Sildenafil (Viagra) is a prescription medicine and may not be suitable for everyone. You should not use sildenafil if you:

  • Take nitrate medicines for chest pain (e.g. glyceryl trinitrate, isosorbide mononitrate), as this can cause a dangerous drop in blood pressure
  • Have recently experienced a heart attack, stroke or severe heart rhythm problem
  • Have very low blood pressure or uncontrolled high blood pressure
  • Have severe liver or kidney disease
  • Have rare eye conditions such as non-arteritic anterior ischemic optic neuropathy (NAION) or retinitis pigmentosa
  • Are allergic to sildenafil or any ingredient in the tablet

Interactions with Other Medicines

Some medicines can interact with sildenafil and may require dose adjustments or medical supervision. Tell your doctor if you are taking:

  • Nitrates or nitric oxide donors – must not be combined with sildenafil
  • Blood pressure medications or alpha-blockers (e.g. doxazosin, tamsulosin) – may increase risk of dizziness or fainting
  • Ritonavir or other HIV protease inhibitors – can increase sildenafil levels in the blood
  • Antifungals (ketoconazole, itraconazole) or antibiotics (erythromycin, clarithromycin) – may require lower doses
  • Other erectile dysfunction treatments (tadalafil, vardenafil, alprostadil) – should not be used simultaneously

Alternatives to Sildenafil tablets

There are various other treatment methods for Erectle Dysfunction (ED) to Sildenafil tablets.25 mg sildenafil

These include other oral medications such as:

  • Tadalafil (Cialis)

Another PDE-5 enzyme inhibitor which increases blood flow to the penis and allows for an easier erection when sexually aroused. Tadalafil lasts longer (36 hours) than Sildenafil in the bloodstream.

  • Vardenafil (Levitra)

Similar to sildenafil in mechanism of action and timeframe of activity

  • Avanafil (Stendra)

Another PDE 5 enzyme inhibitor which gets active very quickly (within 15 minutes), but lasts for only 6 hours.

There are also some non oral medications such as injectables or suppositories. Please speak to your healthcare professional about these options.

Lifestyle modifications such as diet, exercise and smoking or alcohol can also assist in boosting erectile functions.

Please speak to your healthcare provider about appropriate alternatives to sildenafil for you.

How to Store and Handle Sildenafil Safely

Proper storage of tablets sildenafil ensures their effectiveness and safety over time. Keep the medication in its original packaging, away from moisture, heat, and direct sunlight. Do not store it in the bathroom or near radiators. Always check the expiry date before use and keep out of reach of children.

Storage tips:

  • Store at room temperature (below 25°C)
  • Avoid exposure to humidity or extreme heat
  • Do not use expired tablets
  • Keep in a secure, dry location

If you’re unsure about the condition of your medication, consult a pharmacist before use.

Who Should Consider Lower-Dose Sildenafil?

Viagra sildenafil 25 mg is often recommended for men who are new to ED treatment, have mild symptoms, or are more sensitive to medication. It’s also suitable for those with certain health conditions where higher doses may pose risks. Starting with a lower dose allows your healthcare provider to monitor tolerance and adjust if needed.

Ideal candidates for 25 mg dosage:

  • Men over 60 or with mild ED symptoms
  • Patients with liver or kidney concerns
  • Individuals taking interacting medications
  • Those experiencing side effects at higher doses

If you’re considering treatment, ordering sildenafil pills online through Meds For Less offers a discreet, fast, and clinically reviewed process—no in-person visit required.

Written by Qualified Experts

Authored:01/11/2025

Jan Davies

GPhC: 3058401

Pharmacist

MPharm | University of Manchester

No. Sildenafil, including the 25 mg dose, is a prescription-only medicine in the UK. You need a prescription from a doctor or an online consultation before purchasing.

Viagra is the brand name, while sildenafil is the active ingredient. Generic sildenafil works the same way as Viagra but is usually cheaper.

Sildenafil usually starts working within 30–60 minutes. For best results, take it on an empty stomach and about one hour before sexual activity.

The effects of sildenafil can last for up to 4–5 hours. It does not cause a permanent erection—sexual stimulation is still required.

The standard starting dose is usually 50 mg, but 25 mg may be prescribed for older adults, men with medical conditions or those using certain medications. Your doctor will decide what is safest.

Sildenafil should not be taken more than once in 24 hours. Daily use is only recommended if prescribed by a doctor under controlled dosing.

Headache, facial flushing, blocked nose, dizziness and indigestion are common side effects. They are usually mild and pass within a few hours.

Yes, but only from a licensed UK online pharmacy after completing a medical assessment. Avoid websites selling sildenafil without prescription or at unusually low prices.

Small amounts of alcohol are safe, but drinking too much can reduce the effectiveness of the medication and increase dizziness or low blood pressure.

Sildenafil should not be used if you take nitrate medicines for chest pain, have severe heart problems, low blood pressure or recent stroke or heart attack. Always speak to your doctor first.

Store sildenafil in a cool, dry place below 25°C, away from moisture and out of reach of children. Do not use tablets after the expiry date.

Prices vary by pharmacy and quantity, but generic sildenafil 25 mg is usually cheaper than branded Viagra. Online services may offer better prices with prescription included.

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