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Zumenon

Zumenon is a type of oestrogen hormonal replacement therapy (HRT) that comes as an 1mg or 2mg strength oral tablet. HRT (like Zumenon) is used to tackle the symptoms of menopause such as night sweats, hot flushes, and vaginal dryness; additionally, it may also provide fracture protection by supporting bone density. Read on as we go through some commonly asked questions about zumenon tablets.

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What Is Zumenon?

Zumenon is the commercial name for a type of hormone replacement therapy (HRT). More specifically, it is a type of HRT that contains a form of a hormone called oestrogen (this form is called estradiol). For a bit of background, HRT is a treatment for symptoms of menopause such as night sweats, vaginal dryness, hot flushes, and mood swings. The reason why someone might get these symptoms during menopause is because the levels of oestrogen naturally decline when the body gradually stops producing this hormone. This can lead to a hormonal imbalance which can result in the symptoms mentioned. Zumenon is one such option for managing symptoms of menopause and it comes in the form of an oral tablet. If you are experiencing symptoms like hot flushes, night sweats etc., zumenon may be beneficial for you. However, it is always advised that you consult a doctor prior to starting any HRT treatment so that they can assess your situation and medical history comprehensively as well as monitor your response to any HRT treatment they might prescribe.

What Are Zumenon Tablets Used For?

Zumenon tablets are used to help relieve symptoms of menopause. These symptoms come about because of the decline in a hormone called oestrogen. Before we get into how the medication actually works, it may be useful to go through some of the science behind how all of these symptoms in menopause happen in the first place. There is a set number of egg follicles in the ovaries, this is already established at birth. Then at puberty the ovaries release an egg follicle every month, this is when periods start. However, as mentioned there is a set (not unlimited) number of eggs. So gradually with age at some point the ovaries stop releasing eggs and periods stop. Now, the issue is that the cells in the ovaries are actually making most of the oestrogen in the body; thus along with the end of releasing eggs, the cells in the ovaries also stop making as much oestrogen.

The brain senses this decrease in oestrogen levels or hormonal imbalance and tries to release more of other hormones (e.g Luteinizing Hormone, Follicle-stimulating hormone) to encourage the ovaries to release more oestrogen. The effects of low levels of oestrogen can lead to symptoms like night sweats, hot flushes, vaginal dryness, and mood changes. It may be surprising that changes to such a small part in the body like the ovaries can lead to symptoms throughout the body (or systemically). This happens because there are many tissues in the body that have receptors that are sensitive to oestrogen levels.

Zumenon HRT – How It Works

Now that we have discussed the process of how menopause occurs and why it might cause symptoms (e.g night sweats, hot flushes, vaginal dryness), let’s talk through how Zumenon HRT works. So Zumenon is a type of hormone replacement therapy (HRT). Why is hrt zumenon used to manage symptoms of menopause? A key imbalance leading to the symptoms characteristic of menopause is the decline of oestrogen. Zumenon works to relieve menopausal symptoms by supplementing levels of oestrogen to support hormonal balance. It may also help to maintain bone density, this addresses another concern in menopause: weaker bones from the decline in bone density. For women that have a uterus (have not undergone a hysterectomy), your healthcare provider should also prescribe another medication containing progesterone alongside any oestrogen HRT like Zumenon. This helps to decrease the risk of abnormal thickening of the endometrium that can happen with oestrogen supplementation.

The process of oestrogen decline is natural, however that does not make it any less uncomfortable for people who experience the symptoms of menopause. This is another key point to note. Everyone’s experience of menopause can be very different. Some people experience some symptoms, some people have symptoms that significantly disturb their life, and others may not experience many symptoms at all. This not only highlights the individual variation in how menopause is experienced but also why it is important to speak to a medical professional to agree on a treatment plan that is individualised to you and your health background.

Zumenon Dosage & Strengths

For the Zumenon treatment that is right for you, please consult a medical professional before beginning any HRT so that they can assess the risks and benefits of your individual situation. However, for general information, here is an overview of dosage and strength of Zumenon HRT:

Zumenon is a prescription-only HRT medication that comes as an oral tablet and is usually taken once a day. Depending on your symptoms, response to treatment, and past medical history, you may be prescribed a dose of 1mg or 2mg zumenon hrt tablets. The clinical gold standard approach to HRT treatment for menopausal symptoms is to give the lowest dose possible that is effective. The treatment response (including benefits or any side effects) should be monitored by a medical professional and reviewed at regular intervals. This is to ensure as much as possible that the benefits of treatment still outweigh the risks of treatment.

Then, how Zumenon is taken will depend on whether the woman has a uterus/womb.

  • If someone does not have a uterus: Oestrogen-only treatment like Zumenon can be used.
  • If someone has a uterus: Oestrogen-only treatment like Zumenon is not suitable. Your healthcare provider should also prescribe progesterone treatment to reduce the risk of abnormal thickening of the endometrium. This might then mean a regimen of ‘cyclical HRT’ where there is a monthly bleed or ‘continuous HRT’ where there is no monthly bleed. Consult your healthcare provider for further details specific to you.

How to Use Zumenon Tablets Correctly

Always follow your doctor’s instructions on how to take Zumenon. Please note that the treatment dose and regimen may differ between individuals. There are a few things to keep in mind to use Zumenon tablets correctly:

  • Before you start on Zumenon, you should have had a consultation with a doctor to discuss risks and benefits. It is important that you inform your doctor of any medical history (i.e other conditions you might have e.g migraines with aura), any surgical history (e.g hysterectomy), any family history (especially clotting/bleeding problems or cancer) and any medication you take regularly or as needed.
  • Your doctor should organise a follow up appointment or medical review to monitor your response to treatment. Take note of any benefits, side effects, or any changes to your health you notice and bring this information to the medication review. HRT can be a process of trial and error because everyone responds differently to treatment. Your healthcare provider can reassess the treatment and modify it if needed.
  • Take Zumenon tablets consistently, this can help maintain steady levels of the medication in the body. Swallow the Zumenon tablet whole with water. It may be helpful to set an alarm or reminder to take it at the same time every day. If you forget to take a dose, take it as soon as you remember. If it is too close to the time of your next dose then skip the missed dose. Do not take double the dose to make up for any previously missed dose. If you are unsure, please consult your healthcare provider.
  • If you feel like you want to stop the Zumenon tablets, please discuss this with your healthcare provider first. They can assess the situation and advise on how to gradually decrease your dose of medication in a way that is safe for you.

Side Effects & Safety Information

Before starting on Zumenon, there is some safety information you should be aware of including side effects to be aware of and potential longer term risks. For example:

  • More common side effects include: nausea, headaches, leg gramps, and some initial vaginal bleeding/spotting. These side effects may happen initially as you start the Zumenon HRT but they should go away as your body gets used to the medication.
  • Despite the fact that light vaginal spotting/bleeding can be a common side effect, it is crucial that you monitor the bleeding patterns: heavier bleeding, persistent bleeding, unexpected new bleeding, or if anything is concerning you, this should be reported to a medical professional to assess the risk.
  • Endometrial cancer: Oestrogen-only HRT like Zumenon is linked to an increased risk of endometrial cancer if the uterus is intact. It is important that progesterone is prescribed alongside any oestrogen treatment if the uterus is intact. This can help decrease the risk of the abnormal endometrial thickening that can lead to endometrial cancer.
  • Breast cancer risk: there is also a small chance that taking Zumenon longer-term may increase the risk of breast cancer. If you notice any changes to your breasts e.g a lump, nipple changes, or dimples in the skin then you should consult your GP promptly.
  • Deep vein thrombosis risk: call 111 if you notice one of your lower legs/calves is swollen. Especially if it is painful, hot, red, and swollen.
  • Some more rare but serious risks to be aware of include pulmonary embolism, anaphylaxis, and a stroke.

Who Can Take Zumenon Tablets?

Zumenon tablets are suitable for women experiencing symptoms of menopause. The exact regimen of this treatment will then depend on factors like the severity of symptoms and past medical history (e.g previous hysterectomy). Always inform your doctor of any past medical history or new diagnoses and attend your HRT medication reviews. This provides a space to discuss any concerns, monitor response to treatment, and modify the treatment plan as needed. Some examples of groups where Zumenon may not be safe include:

  • Active cancer or past cancer
  • History of a blood clot in a vessel e.g Deep Vein Thrombosis
  • High stroke or cardiovascular event risk

Buy Zumenon Online & Price in the UK

It is now possible to bypass the potential long NHS waits and buy Zumenon online. However, there are a few things to note before you go for this.

  • Make sure you select a reputable and registered online provider. This will help to ensure the safety and quality of the medication you are purchasing.
  • Zumenon is a prescription-only medication; you will need a valid prescription from a NHS doctor or a private doctor. On the NHS, Zumenon will cost the standard prescription charge while the price from private healthcare providers can vary significantly. Some private healthcare providers may charge for the consultation and the prescription alongside the actual Zumenon medication. In some cases you may be eligible for a HRT prescription prepayment certificate that can make HRT treatment cheaper.

If you have a uterus, it is unsafe to take Zumenon (an oestrogen medication) on its own. Your doctor should prescribe a suitable progesterone medication (e.g Utrogestan) alongside Zumenon to reduce the risk of endometrial cancer.

Currently, the research does not say that Zumenon leads to weight or appetite changes. A possible side effect is fluid retention when starting treatment which can look like weight gain. However, the hormonal changes during menopause can mean that weight gain during this time is not unusual.

This can vary from person to person. Many women notice an improvement in symptoms after a few weeks but generally it may take up to 3 months to see the full benefit.

Yes, oestrogen supplementation like Zumenon can help to reduce the loss in bone density that happens during menopause. 

If you want to stop Zumenon, it is best to discuss it with your healthcare provider. They can assess the situation and, if appropriate, advise on how to gradually stop Zumenon in a way that helps to decrease the chances of the menopausal symptoms returning.

Yes, surgical menopause (e.g oophorectomy i.e removing both ovaries) can lead to a very sudden drop in oestrogen levels. This may lead to uncomfortable symptoms and require oestrogen supplementation such as Zumenon.

Currently the research and clinical guidelines do not put forward any natural alternatives that act in the same way as Zumenon. However, there are many non-hormonal interventions and lifestyle changes that can help reduce symptoms of menopause. For example, lubricants (for vaginal dryness), weight management, and cooling methods have been shown to help relieve mild symptoms of menopause. 

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