Orlistat is a medication that limits the amount of fat you absorb from your diet by blocking some of the digestive enzymes in your intestines.
Here’s what you need to know about taking this weight-loss drug:
Lipase is an enzyme that breaks down fats in your diet and turns them into digestible fatty acids. The blockage of lipase activity by Orlistat means that fat is not readily digested and can’t be used for energy. Instead, it goes to waste.
The effects of Orlistat on weight loss are most frequently related to slowing digestion and food absorption rather than changes in the appetite centre (appetite). If you eat more food because you have a slower digestion process, you will retain more calories.
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But remember, the effects of Orlistat on weight loss are most frequently related to slowing digestion and food absorption rather than changes in the appetite centre (appetite). If you eat more food because you have a slower digestion process, you will retain more calories.
The “blocker” aspect of the drug, which is why you take it, means that it interferes with the action of your body’s enzymes and blocks the absorption of fat from your diet. The official term for this is “statin.”
Orlistat decreases the amount of fat absorbed by about one-third and reduces total dietary cholesterol by about 30 per cent. It increases the fat secreted by the liver, but this is most likely a side effect and not an intended effect.
Orlistat does not lower cholesterol levels at all, nor does it reduce your risk of heart disease or stroke. But that doesn’t mean it’s not helpful for weight loss. Orlistat helps you lose weight and should be taken with the other medications in your treatment program.
Because it prevents the absorption of fat, Orlistat also reduces the calories from fat that you get from eating. Diets high in fat are associated with weight gain. A diet low in fat and high in protein and complex carbohydrates can help you lose weight.
In addition to weight loss, Orlistat controls your appetite, which can help you lose weight. In one study of obese people, Orlistat helped them lose an average of 15 pounds after three months on a diet.
Orlistat may also be helpful for people with diabetes who have high cholesterol and are at risk for heart disease or stroke. In a study of 257 people with diabetes aged 50 and older, Orlistat reduced the risk of heart attack by 25 per cent and stroke by 34 percent compared with a placebo.
The most common side effect is flatulence, which you may not like. But it’s usually mild and doesn’t interfere with medications you take to control blood sugar. Orlistat also causes problems in some people with irritable bowel syndrome (IBS) or gastroesophageal reflux disease (GERD).
Because of the way Orlistat works, it can affect the medications that you take. Orlistat can make some drugs broken down by stomach acid less effective, including the antibiotics ampicillin and tetracycline, as well as warfarin (a blood thinner).
You may need to change or stop taking these drugs while on Orlistat.
Orlistat is a weight-loss drug that helps you lose weight by blocking fat digestion from your diet. It’s usually combined with reduced calorie intake and increased physical activity.
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