Doxycycline and Benzoyl Peroxide Gel


Doxycycline and Benzoyl Peroxide gel (generic Acnecide) are both used to treat mild to moderate acne symptoms. They both work to kill the bacteria that cause acne and reduce the appearance of spots.

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About Doxycycline and Benzoyl Peroxide Gel

How should I use Doxycycline and Benzoyl Peroxide gel?

Doxycycline should be taken once a day with a meal, plenty of water, and while sitting or standing. It is also critical to allow some time between taking the tablet and going to bed.

Benzoyl Peroxide gel (generic Acnecide) should be applied once or twice a day to clean, dry skin, depending on how your skin reacts to the treatment.

How does Doxycycline and Benzoyl Peroxide gel work?

Doxycycline is an antibiotic that works by killing the bacteria responsible for acne. Because it is antibacterial, Benzoyl Peroxide gel also works to eliminate the bacteria that cause acne. Furthermore,

Keratin, a protein that is part of the skin’s structure, is broken down by Benzoyl Peroxide gel. This means it dissolves blackheads and whiteheads while also unclogging sebaceous glands.

Is this treatment combination effective?

This acne treatment combination is most effective for people who have papules (small red bumps), pustules (red bumps with white tips), and nodules or cysts (much larger lumps which are more likely to cause scarring).

Because both medications are antibacterial, they are an effective treatment for addressing the root cause of acne. Benzoyl Peroxide gel will also help to clear up the appearance of acne by reducing inflammation and redness.

Do Doxycycline or Benzoyl Peroxide gel have any side effects?

Both Doxycycline and Benzoyl Peroxide gel are likely to make the skin more sensitive to sunlight; therefore, sunbeds and sunlamps should be avoided, and an SPF of at least 30 should be worn.

Doxycycline can cause nausea, abdominal pain, dizziness, and shortness of breath in some people. A mild burning sensation, redness, dryness, and peeling skin may occur when using Benzoyl Peroxide gel. It is also important to remember that Benzoyl Peroxide gel will bleach any hair or fabric it comes into contact with.

See the patient information leaflets for Doxycycline and Benzoyl Peroxide for more information on side effects and proper use.

Is it safe to use Doxycycline or Benzoyl Peroxide gel while pregnant or breastfeeding?

While pregnant or breastfeeding, neither Doxycycline nor Benzoyl Peroxide gel should be used.

Will either of these medications interact with other medicines?

Doxycycline can impair the effectiveness of other medications, so please inform us of any medications you are taking when you request this treatment.

Avoid using Benzoyl Peroxide gel in conjunction with any medications containing high alcohol concentrations, such as tretinoin, isotretinoin, or tazarotene, as this may cause irritation.

Acne Treatment Alternatives

Some women may be prescribed the oral contraceptive Co-cyprindiol in addition to a topical solution to treat their acne instead of taking oral antibiotics. Some acne sufferers may be given a cream or gel to help them deal with their condition.

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