Doxycycline and Epiduo Gel


Both medications are prescribed to treat moderate acne and work to kill the bacteria that cause acne as well as break down the outer layer of skin, blackheads, and whiteheads.

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About Doxycycline and Epiduo Gel

How should I take Doxycycline and use Epiduo gel?

Doxycycline should be taken with plenty of water, preferably with a meal, and always while sitting or standing.

Once a day, apply Epiduo gel in a thin layer to the affected area. Apply it after cleansing and drying your face and before going to bed. After applying, make sure to thoroughly wash your hands because it will bleach fabric, towels, and hair.

How do Doxycycline and Epiduo work?

Doxycycline is an antibiotic that works by killing the bacteria responsible for acne. Because Epiduo gel contains Adapalene and Benzoyl Peroxide, it works in two different veins.

Adapalene is a retinoid that works to break down blackheads and whiteheads while also reducing inflammation and preventing the formation of microcomedones (the precursor to acne lesions). Benzoyl Peroxide softens and peels the skin’s outer layer while also killing acne-causing bacteria.

Is this combination treatment going to be effective?

This combination of medications is likely to be effective for people who have pustules (small red bumps filled with pus), nodules, and cysts (larger lumps). Its ability to break down skin processes that cause acne, combined with its antibacterial action, makes it a well-rounded treatment for those suffering from mild to moderate acne.

Is there any harm in taking Doxycycline or applying Epiduo gel?

Both of these medications are likely to make the skin more sensitive to sunlight, so it is critical that you protect yourself from the sun and use an appropriate sun cream.

Doxycycline causes nausea, tummy pain, shortness of breath, racing heartbeat, and dizziness when standing up in some people. The most common side effects of epiduo are a mild burning sensation, redness, dryness, and peeling of the affected area.

See the patient information leaflets for Doxycycline and Epiduo for more information on side effects and proper use.

Is it safe to use Doxycycline or Epiduo gel while pregnant or breastfeeding?

Doxycycline and Epiduo gel should not be used while pregnant or breastfeeding.

Will this medication interact with any other medications I'm taking?

Doxycycline may reduce the effectiveness of other medications, so please inform our clinicians of any other medications you are taking.

While using Epiduo gel, you should avoid using any acne products that contain Benzoyl Peroxide or retinoids, as well as cosmetics that irritate, dry, or exfoliate the skin.

Acne Treatment Alternatives

Instead of taking oral antibiotics, some women may be prescribed the oral contraceptive Co-cyprindiol in conjunction with an acne cream or gel. Some people with acne may only be prescribed a cream or gel.

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