Doxycycline and Epiduo Gel

Both medications are prescribed to treat moderate acne and work to kill the bacteria that cause acne as well as break down the outer layer of skin, blackheads, and whiteheads.

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*Product images are for illustrative purposes only, and you may receive a different licensed alternative.
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Doxycycline should be taken with plenty of water, preferably with a meal, and always while sitting or standing.

Once a day, apply Epiduo gel in a thin layer to the affected area. Apply it after cleansing and drying your face and before going to bed. After applying, make sure to thoroughly wash your hands because it will bleach fabric, towels, and hair.

Doxycycline is an antibiotic that works by killing the bacteria responsible for acne. Because Epiduo gel contains Adapalene and Benzoyl Peroxide, it works in two different veins.

Adapalene is a retinoid that works to break down blackheads and whiteheads while also reducing inflammation and preventing the formation of microcomedones (the precursor to acne lesions). Benzoyl Peroxide softens and peels the skin’s outer layer while also killing acne-causing bacteria.

This combination of medications is likely to be effective for people who have pustules (small red bumps filled with pus), nodules, and cysts (larger lumps). Its ability to break down skin processes that cause acne, combined with its antibacterial action, makes it a well-rounded treatment for those suffering from mild to moderate acne.

Both of these medications are likely to make the skin more sensitive to sunlight, so it is critical that you protect yourself from the sun and use an appropriate sun cream.

Doxycycline causes nausea, tummy pain, shortness of breath, racing heartbeat, and dizziness when standing up in some people. The most common side effects of epiduo are a mild burning sensation, redness, dryness, and peeling of the affected area.

See the patient information leaflets for Doxycycline and Epiduo for more information on side effects and proper use.

Doxycycline and Epiduo gel should not be used while pregnant or breastfeeding.

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