Sumatriptan is a migraine treatment that comes in the form of a tablet. It should be used in conjunction with over-the-counter pain relievers. It is the treatment of choice when used in this manner.

About Sumatriptan

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Using Sumatriptan

When the headache phase of your migraine starts, take 1 tablet. Wait until you no longer have an aura (visual disturbance) before taking Sumatriptan.

If your migraine isn’t completely gone or has returned after 2 hours, take another tablet. This can be done every two hours for a total of four times. Take no more than 300mg Sumatriptan in a 24-hour period.

How does it work

Although no clear cause has been identified, one theory is that migraines are caused by blood vessel dilation (widening), which causes swelling and pressure, resulting in pain and neurological symptoms. Another possibility is that certain chemicals in the brain become more active, causing parts of the brain to send out confusing signals, resulting in symptoms.

Sumatriptan constricts these blood vessels while also reducing the release of certain brain chemicals that occur during a migraine attack, alleviating symptoms.

Side effects

Feeling drowsy or dizzy, nausea and vomiting, shortness of breath, flushing (feeling extremely hot) and muscle aches are all possible side effects. Pain or tightness in the chest is a less common symptom. If your chest pain is severe and not going away, see a doctor right away. Alterations in liver function, seizures, tremors, visual disturbances, and severe allergic reactions are all possible but rare side effects.

See the patient information leaflet for a complete list of side effects and how to use it correctly. If you’re feeling particularly ill or experiencing severe side effects, go to your nearest A&E department or dial 999.

Strength and dosage

Sumatriptan tablets come in 50mg and 100mg strengths. It’s common practice to begin with the lowest dose. If this doesn’t work, your doctor might prescribe the 100mg tablets. Take no more than 300mg of Sumatriptan in a 24-hour period.


Within 2 hours after taking Sumatriptan, your migraine symptoms should improve.

Sumatriptan can be combined with the following treatments to provide the best results. Please consult with your pharmacist to ensure that they are appropriate for you.

Paracetamol 500mg 2 tablets, up to 4 times daily; aspirin 300-900mg, up to 4 times daily; or ibuprofen 400mg, up to 4 times daily

Buccastem M 3mg twice daily as an anti-sickness supplement. These tablets are intended to be used under the tongue. They’re especially useful if vomiting is one of your migraine symptoms because they don’t require swallowing.

Sumatriptan: Important Information

When treating a migraine attack, do not combine Sumatriptan with another triptan. Sumatriptan should not be taken every day because it can cause a medication overuse headache. You should see a doctor right away if your headache becomes significantly worse or if you develop any unusual symptoms.

Safety: taking other medicines

Sumatriptan, like any other medication, can interact with other medications, which can be dangerous at times. This is why it’s critical that you tell us about any prescription, over-the-counter, or recreational medications you’re taking so that we can safely prescribe Sumatriptan.

Sumatriptan should not be combined with any other prescription medication without first consulting your doctor. You can also send us a message through your Patient Record.

Treatment options

For migraines, we can also prescribe Rizatriptan, which may be more appropriate for you.

Other pain relievers and anti-sickness medications will need to be prescribed by your doctor. Metoclopramide 10mg, Migramax (aspirin 900mg plus metoclopramide 10mg), and Paramax are some of them (paracetamol 500mg plus metoclopramide 5mg).

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