Co-cyprindiol and Azelaic Acid Gel


For women with acne, a combination of Co-cyprindiol (also known as Dianette or Clairette) and Adapalene gel (generic Differin) can help to minimise the look and production of acne.

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About Co-cyprindiol and Azelaic Acid Gel

How do I use Azelaic Acid gel and Co-cyprindiol?

Co-cyprindiol (commonly referred to as Dianette or Clairette) is a combined oral contraceptive pill that should be taken on the first day of your period. It is to be taken at the same time every day for 21 days, followed by a seven-day break. When taken in this manner, it will also serve as a form of contraception.

Azelaic Acid (generic Finacea) acne gel should be applied twice daily, preferably in the morning and evening. It should be used after cleansing the skin with a gentle cleanser.

How does this acne treatment work?

Azelaic Acid gel reduces the amount of sebum (oil) produced by the skin, which results in fewer acne-causing bacteria and fewer blocked pores because sebum is their food source. Co-cyprindiol is a contraceptive pill that helps to block acne-causing hormones.

The combination of these two medications works to treat existing acne while also preventing new acne from forming.

Is this acne treatment combination effective?

Azelaic Acid gel is most effective for treating acne with papules (small red bumps) and pustules (white-tipped spots), as well as for those with sensitive skin. Co-cyprindiol is beneficial for women who suffer from hormonal acne because it inhibits the hormones that are most responsible for acne flare-ups.

If you want to see the effects of acne treatments, you must use both treatments optimally.

Is there any harm in using Co-cyprindiol or Azelaic Acid gel?

Co-cyprindiol, like many medications, can cause side effects in some people. Women may experience changes in mood, weight gain, headaches, and nausea. When using Azelaic Acid gel, some people may experience redness, dry skin, and irritation.
See the patient information leaflets for Co-cyprindiol and Azelaic Acid gel for more information on side effects and proper use.

Is it safe to use Azelaic Acid gel while pregnant or breastfeeding?

Co-cyprindiol should not be used if you are pregnant or breastfeeding. Azelaic Acid gel should not be used while pregnant or breastfeeding, but it can be used if it is not applied to the chest.

Will this acne treatment interfere with any other medications I'm taking?

You should avoid using other topical creams or gels on the affected area while using Azelaic Acid gel to treat your acne.

Other medications may interfere with Co-effectiveness cyprindiol’s and ability to protect against pregnancy. You should inform us about any other medications you are taking so that we can safely prescribe the best acne treatment for you.

Acne Treatment Alternatives

Instead of the contraceptive pill Co-cyprindiol, you may be prescribed oral antibiotics in addition to a topical gel or cream to treat your acne. Topical medications can also be prescribed on their own.

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